Gulators ASXL1, ASXL2 and ASXL3: a convergence of proteomics and epigenetics > 자유게시판

• 목록
• 게시판 리스트 옵션
  • 수정
  • 삭제

Gulators ASXL1, ASXL2 and ASXL3: a convergence of proteomics and epigenetics for translational medication. Skilled Rev Proteomics. 2015;twelve:317?eight. fifty eight. Balasubramani A, Larjo A, Bassein JA, Chang X, Hastie RB, Togher SM, et al. Cancer-associated ASXL1 mutations might act as gain-of-function mutations with the ASXL1-BAP1 Lenvatinib advanced. Nat Commun. 2015;6:7307. 59. Inoue D, Matsumoto M, Nagase R, Saika M, Fujino T, Nakayama KI, Kitamura T. Truncation mutants of ASXL1 noticed in myeloid malignancies are expressed at detectable protein stages. Exp Hematol. 2016;44:172?. sixty. Abdel-Wahab O, Adli M, LaFave LM, Gao J, Hricik T, Shih AH, et al. ASXL1 mutations encourage myeloid transformation via loss of PRC2-mediated gene repression. Most cancers Mobile. 2012;22:180?three. 61. Abdel-Wahab O, Gao J, Adli M, Dey A, Trimarchi T, Chung YR, et al. Deletion of Asxl1 final results in myelodysplasia and intense developmental problems in vivo. J Exp Med. 2013;210:2641?9. 62. Micol JB, Pastore A, Inoue D, Duployez N, Kim E, Lee SC, et al. ASXL2 is vital for haematopoiesis and functions as a haploinsufficient tumour suppressor in leukemia. Nat Commun. 2017;8:15429. sixty three. Hoischen A, van Bon BW, Rodr uez-Santiago B, Gilissen C, Vissers LE, de Vries P, et al. De novo nonsense mutations in ASXL1 cause Bohring-Opitz syndrome. Nat Genet. 2011;forty three:729?1. 64. Edgar RC. Muscle: various sequence alignment with higher precision and high throughput. Nucleic Acids Res. 2004;32:1792?. 65. Rice P, Longden I, Bleasby A. EMBOSS: the eu molecular biology open up computer software suite. Trends Genet TIG. 2000;sixteen:276?.Dinan et al. Biology Immediate (2017) twelve:Web site sixteen of66. Guindon S, Gascuel O. An easy, quickly, and precise algorithm to estimate substantial phylogenies by utmost probability. Syst Biol. 2003;52:696?04. 67. Li X, Romero P, Rani M, Dunker AK, Obradovic Z. Predicting protein dysfunction for N-, C-, and inner locations. Genome Inform Ser Workshop Genome Inform. 1999;ten:thirty?0. 68. Sievers F, Higgins DG. Clustal omega, precise alignment of really significant quantities of sequences. Procedures Mol Biol Clifton NJ. 2014;1079:one zero five?6. 69. Bernhart SH, Hofacker IL, Will S, Gruber AR, Stadler PF. RNAalifold: enhanced consensus framework prediction for RNA alignments. BMC Bioinformatics. 2008;9:474. 70. Rivas E, Eddy SR. A dynamic programming algorithm for RNA construction prediction which includes pseudoknots. J Mol Biol. 1999;285:2053?8. seventy one. Langmead B, Trapnell C, Pop M, Salzberg SL. Ultrafast and memory-efficient alignment of small DNA sequences to the human genome. Genome Biol. 2009;ten:R25. seventy two. Altschul SF, Gish W, Miller PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/8627573 PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/22316373 W, Myers EW, Lipman DJ. Standard nearby alignment lookup resource. J Mol Biol. 1990;215:403?0. seventy three. Zerbino DR, Birney E. Velvet: algorithms for de novo quick read assembly employing de Bruijn graphs. Genome Res. 2008;18:821?. seventy four. Hurst LD. Preliminary evaluation of your impact of microRNA-mediated regulation on coding sequence evolution in mammals. J Mol Evol. 2006;sixty three:174?two. 75. Schattner P, Diekhans M. Regions of maximum synonymous codon collection in mammalian genes. Nucleic Acids Res. 2006;34:1700?0. seventy six. Parmley JL, Chamary JV, Hurst LD. Evidence for purifying range in opposition to synonymous mutations in mammalian exonic splicing enhancers. Mol Biol Evol. 2006;23:301?. seventy seven. Savisaar R, Hurst LD. Both equally routine maintenance and avoidance of RNA-binding protein interactions constrain coding sequence evolution. Mol Biol Evol. 2017;34:1110?six. 78. Lin MF, Kheradpour P, Washietl S, Parker BJ, Pedersen JS, Kellis M. Locating protein-coding sequences beneath s.