Where no-rec means no recurrence cases and rec corresponds to recurrence > 자유게시판

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Where no-rec means no recurrence cases and rec corresponds to recurrence cases meanwhile the p-value corresponds to the t-test where the mean ages for recurrence and no recurrence are comparedAge All No-Rec Rec. Min. 24.00 24.00 31.00 Median PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/14960617 45.00 45.00 37.50 Mean 3rd Qu. 46.21 47.18 42.75 58.00 58.00 49.25 Max. 77.00 77.00 68.00 N 36 28 8 0.4107 p-valueinterval contains the value one i.e. we cannot reject that there is no association between the variable considered and pterygia recurrence. Let us consider the variable giving us whether the pterygium has recurred after the one year follow-up, the one-year recurrence (1 3-Amino-1H-indazole-4-carbonitrile = recurrence and 0 = non-recurrence). Our major aim will be to study the influence of some covariables over the one year recurrence. The covariables considered are: age (AGE), gender (GENDER: 1, male; PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/21715270 0, female), race (R, Caucasians and Hispanics), latitude (LAT), altitude (ALT), workdays sun exposure (WDE), non-workdays sun exposure (NWDE), primary vs recurrent pterygia (PR), pterygium type (PT: 1, 2 and 3 according to Tan classification), wide base (WB: less or greater than 5 mm), surgical technique (ST: fibrin glue and sutures), miss-apposition (MA: 0, not and 1, yes) and protective measures (PM: 0, none; 1, hat; 2, sunglass). A logistic regression has been applied where the binary response is the one-year recurrence. The covariables 3-(2,2,2-Trifluoroethoxy)aniline hydrochloride remaining in the model after variable selection are GENDER, WDE, NWDE and WB. Table 3 shows the parameter estimates and the p-values testing a null coefficient. Figure 1 displays the probability of recurrence during the one year follow-up for different values of WDE (from one to ten hours/day of sun exposure on workdays), NWDE equal to the mean value observed, and the variables GENDER and WB. Figure 1 shows four lines that from top to bottom correspond to male without wide base, male with wide base, female without wide base and female with wide base. Note that the main differences correspond to gender. The differences due to WB are clearly smaller. For each eye our protocol gives us the time from surgery to recurrence. In fact, we are dealing with interval censored data because for each patient the time interval when recurrence appears is known. We have checked each patient at days two and seven, two months, six months and one year. This interval censored data has been used to estimate the survival function S(t) (for each time t, the fraction of patients with a time to recurrence greater than t). Figure 2 (left) displays the survival function estimated. The recurrences mainly appear between 2 and 6 months after surgery. The interval censored survival times have been compared (log-rank two sample test) for gender and WB. A significant p-value is observed for gender (p<0.001) and non significant for WB (p=0.64). Figure 2 (right) displays the estimated survival functions considering the gender. A total of thirty-six patients completed the 12-month follow-up period and eight of them (22 ) presented a recurrence within a year post-operatively. The most important variable influencing surgical success is gender. All patients that suffered a recurrence were male. The second most important variable is the hours that the subject was exposed to sun radiation, mainly during workdays,Torres-Gimeno et al. BMC Ophthalmology 2012, 12:38 http://www.biomedcentral.com/1471-2415/12/Page 4 ofTable 2 Columns "Non recurrence" and "Recurrence" correspond to the number of cases without and with recurrence respect.